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In the Pipeline: Cabozantinib Shown to Control Tumors and Bone Metastases

May 23, 2011

By Jennie Smith

The experimental drug cabozantinib achieved high rates of disease control and shrunk or eliminated bone metastases in a range of advanced cancers, according to results from a phase II trial.

Blood Test For Breast Cancer?

May 23, 2011

Researchers at Georgetown Lombardi Comprehensive Cancer Center say the amount of circulating tumor cells (CTCs) in the blood is a "powerful predictor" and reliable for aiding physicians when they assess treatment benefit for patients with metastatic breast cancer.

Nexavar In Combination With Chemotherapy Improves Progression-Free Survival In Patients With Advanced Breast Cancer In Phase 2 S

May 23, 2011

Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. today announced results from a Phase 2b trial evaluating Nexavar® (sorafenib) tablets in patients with locally advanced or metastatic breast cancer

Genentech Appeals to FDAs Regulatory Flexibility on Avastin

May 19, 2011

By Mary Jo Laffler

Genentech’s advance summary of evidence and arguments for the Food and Drug Administration’s upcoming hearing on the agency’s proposed withdrawal of the metastatic breast cancer approval for Avastin shows that the company is trying to keep the focus on the additional confirmatory trial it proposes to conduct.

Should a Mother Lose Custody of Her Kids Because She Has Cancer?

May 13, 2011

By Bonnie Rochman

Alaina Giordano was already engaged in a battle royale, fighting Stage 4 breast cancer, when her struggle intensified recently: a judge ruled that the N.C. woman must give up custody of her two children to her husband, who lives in Chicago, in part because "children who have a parent with cancer need more contact with the non-ill parent."

 

 

Breast cancer cells utilize tissue stem cell EMT for tumor metastasis

May 10, 2011

By University of North Carolina School of Medicine

Researchers at the University of North Carolina at Chapel Hill School of Medicine, after isolating normal stem cells that form the developing placenta, have given them the same properties of stem cells associated with an aggressive type of breast cancer. The scientific first opens the door for developing novel targeted therapies aimed at triple negative breast cancer.

4th International Symposium On Cancer Metastasis And The Lymphovascular System

May 10, 2011

By California Pacific Medical Center

Novel therapies for breast cancer, melanoma, and other solid tumors, and discussions of the microenvironment around metastatic disease, will be among the topics covered in presentations at the 4th International Symposium on Cancer Metastasis and the Lymphovascular System

Chemo Combo for Metastatic Breast Cancer May Help Previously Treated Patients

May 3, 2011

By Anne Azvolinsky, PhD

A 33-patient Phase 1/2 study in Europe published in the European Journal of Cancer (doi:10.1016/j.ejca.2011.01.001) has shown that a new chemotherapy combo of a novel taxoid, cabazitaxel, and capectiabine shows promise in previously treated metastatic breast cancer patients. The combination also had a good safety profile, which means that it warrants more extensive clinical trials.