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Complementary & Alternative Medicine Clinical Trials Influence Breast Cancer Care

August 30, 2012

By BreastCancerTrials.org

Is low-level laser therapy an effective lymphedema treatment? Can acupressure reduce cancer related fatigue? Might green tea reduce breast cancer risk? These are among the more than 50 research questions now being studied in complementary and alternative medicine (CAM) breast cancer trials throughout the United States.

Modeling metastasis

August 24, 2012

Cancer metastasis, the escape and spread of primary tumor cells, is a common cause of cancer-related deaths. But metastasis remains poorly understood. Studies indicate that when a primary tumor breaks through a blood vessel wall, blood's "stickiness" tears off tumor cells the way a piece of tape tears wrapping paper.

Until now, no one knew the physical forces involved in this process, the first step in metastasis. Using a statistical technique employed by animators, scientists created a new computer simulation that reveals how cancer cells enter the bloodstream. The researchers present their work in a paper accepted to the American Institute of Physics (AIP) journal Physics of Fluids.

 

Denosumab superior to zoledronic acid for breast cancer patients with bone metastases

August 14, 2012

By Science Codex

Treatment with denosumab resulted in a greater reduction in skeletal-related events in patients with breast cancer that spread to the bones compared with zoledronic acid, while also maintaining health-related quality of life, according to the results of a phase III study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

The Media’s Pink-Ribbon Problem: Coverage Is Skewed, Study Says

August 13, 2012

By Abigail Pesta, The Daily Beast

As the media chew on news that Nancy Brinker, the controversial founder of Susan G. Komen for the Cure, will step down as chief executive after a brutal year, a new study says progress in fighting breast cancer is unacceptably slow, public perception is skewed-and the media are partly to blame.

 

Research Unravels New Ways to Treat HER2-Positive Breast Cancer

August 10, 2012

By Elizabeth Whittington, Cure

Perjeta and an increasing arsenal of investigational agents, combinations could significantly improve survival rates in HER2-positive breast cancer.

When Debra Tincher received a diagnosis of stage 2 breast cancer in 1997, testing for HER2-positive breast cancer wasn't standard. She went through treatment and was cancer-free for more than 10 years, teaching kindergarten in Hamilton, Ohio.

 

 

Research suggests breast cancer cells have discerning tastes

August 7, 2012

If detected early, most cases of breast cancer are curable. But if the tumour has metastasized - or spread to a site outside of the breast - cure rates decline. A team of researchers from Lawson Health Research Institute and Western University have received $449,733 from the Canadian Breast Cancer Foundation - Ontario Region to study a rare subpopulation of tumour cells called cancer stem cells (CSCs) in hopes of uncovering the mystery behind metastasis.

 

TRPM7 Protein Key to Breast Cancer Metastasis in Animal Models

August 7, 2012

By ScienceDaily

The protein transient receptor potential melastatin-like 7 (TRPM7) is a critical determinant of breast cancer cell metastasis, according to study results published in Cancer Research, a journal of the American Association for Cancer Research.

 

Anti-Estrogen Combo Better for Late Breast Cancer

August 1, 2012

By Salynn Boyles

Older women with the most common type of metastatic breast cancer may soon have a new treatment option that may improve their survival.

A new study shows that postmenopausal women with advanced disease treated with a combination of two anti-estrogen therapies lived longer than women who took one drug followed by another.