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A Mainstay of Breast Cancer Treatment, Cytotoxics Class Must Grow

November 29, 2012

By Julian Kaye, OncLive

Despite the trend toward targeted therapies, cytotoxic drugs remain a mainstay of metastatic breast cancer (MBC) treatment, and new therapies in that class are needed, according to Joyce A. O’Shaughnessy, MD.

Mammograms Are Not Effective In Lowering Breast Cancer Death Rates

November 25, 2012

By MedNews Today

During the last 30 years, millions of women have been diagnosed with breast cancer. Although screenings with mammograms are often used, the prevalence of metastatic breast cancer has not changed and there has been no reduction in the rate of cancer being diagnosed in late stages, according to a recent study published in the New England Journal of Medicine conducted by researchers at The Dartmouth Institute for Healthy Policy & Clinical Practice in Lebanon, N.H.

Breast cancer indicator protein discovered, U. researchers say

November 13, 2012

By Loully Saney

University researchers have discovered a protein that controls tumors in breast cancer, a possible path toward the diagnosis and treatment of the disease. The lactation protein, known as Elf5, inhibits metastasis, the spread of the disease to other organs.

 

In Breast Cancer, Targeted Agents Boost Hormonal Therapies

November 13, 2012

By Anita T. Shaffer

Although hormonal therapy has been long established in the treatment of breast cancer, novel combinations with targeted agents show promise for improved outcomes and are likely to become part of a new paradigm for managing patients.

 

Microscopic spheres kill metastatic breast cancer

November 8, 2012

By Ed Yeates, KSL

SALT LAKE CITY -- University of Utah professor Beverly Brehl was back teaching her class only seven days after doctors placed microscopic cancer-killing spheres into her bloodstream.

With metastasized breast cancer now in her liver, doctors at the Huntsman Cancer Institute decided to try a different kind of attack.

 

Laser-light testing of breast tumor fiber patterns helps show whose cancer is spreading

November 2, 2012

Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue samples and to help tell if the cancer has spread.

 

Drug Combo Tackles Brain Mets in Breast Cancer

November 2, 2012

By Crystal Phend, Senior Staff Writer, MedPage Today

The combination of the biologic lapatinib (Tykerb) and capecitabine (Xeloda) chemotherapy appears to shrink brain metastases from HER2-positive breast cancer without need for radiation, a phase II trial showed.

Two-thirds of patients saw their previously-untreated brain lesions shrink by at least half with the treatment regimen, Thomas Bachelot, MD, of the Centre Léon Bérard in Lyon, France, and colleagues found in the LANDSCAPE trial.