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New insights into PI3K pathway and cancer metabolism

January 29, 2016

By MedicalXpress

This study demonstrates that PI3K is a master regulator integrating a cancer cell's architecture and its metabolism.

Groundbreaking Collaborative Breast Cancer Study Aims to Unlock the Doors of Individualized Patient Care with Big Data

January 28, 2016

By National Comprehensive Cancer Network

Thirty-two researchers from 14 institutions joined forces to identify personalized treatment options for a patient with metastatic triple-negative breast cancer.

African American Women and Metastatic Breast Cancer

January 19, 2016

By You Tube Video: Katherine O'Brien, MBCN

African American Women and Metastatic Breast Cancer

Worldwide 500,000 die each year from Metastatic Breast Cancer, with 40,000 in the US alone. According to the CDC, back women have lower incidence rate of mbc compare to white women, but a higher number dying in every age group.

Is Metastatic Breast Cancer Really Incurable?

January 16, 2016

By Dr Susan Love Blog

Each time I check Facebook, it seems we have lost another woman or man to metastatic breast cancer. It’s important to focus our efforts on how to prevent breast cancer all together. But as we work toward that goal, it’s equally important to figure out how to cure metastatic disease.

That’s why I was delighted to see a trio of pieces in the January 2016 issue of Journal of Oncology Practice that re-examines the question of whether we can cure metastatic breast cancer.

George Sledge, chief of medical oncology at Stanford University School of Medicine, wrote the primary article, a provocative discussion about how we think about metastases and how we define cure.

Are you “cured” if you are disease-free for five or 10 years? What about if you are living with metastatic breast cancer but die from something unrelated to the cancer? If metastatic breast cancer could be controlled, but not eliminated, like diabetes or HIV, would that be a cure? 

Importantly, Dr. Sledge reminds us there are actually a few people we are curing right now. This includes women and men who have microscopic disease in other organs at the time of diagnosis, what were currently refer to as micro-metastatic disease.

Living With Cancer: A Broken Covenant With Patients

January 15, 2016

By NY Times Wellness Blog: Susan Gubar

As a cancer patient whose life has been miraculously extended by a clinical trial, I was shocked by Charles Piller’s Dec. 13 essay “Law Ignored, Patients at Risk” in STAT News on lapses in reporting the results of such trials. My first response was to ask: Is he a reputable journalist? Is the online venue in which the article appears legit? When the answer to each of these questions came back a resounding yes, I began worrying that cancer doctors and patients have been imperiled by irresponsible researchers.

Moonshot’ to Cure Cancer, to Be Led by Biden, Relies on Outmoded View of Disease

January 15, 2016

By NY Times: Gina Kolata and Gardiner Harris

Last Friday a group of 15 cancer researchers cut short a meeting at the Food and Drug Administration. The reason: They had been invited to Vice President Joseph R. Biden’s office to discuss his “moonshot” to cure cancer.

“We had no idea what was coming,” said Dr. George D. Demetri, director of the Ludwig Center at Harvard and a professor of medicine at Harvard’s Dana-Farber Cancer Institute.

It turned out the vice president was out of town that day, but his staff wanted to know: What could Mr. Biden do in his remaining year in office, and over the long term, to advance cancer research and ultimately cure the disease?The idea that a concerted government push can lead to a “cure” for cancer is nearly a half century old, stretching back to President Nixon’s failed “War on Cancer.” The latest, which President Obama formalized in his State of the Union address on Tuesday, has a deeply emotional tinge. Mr. Biden’s son Beau died of brain cancer in May, and the vice president’s very public mourning and call for a “national commitment to end cancer as we know it” as he announced his decision not to run for president has moved and captivated Washington.

Cancer Lifer Holley Kitchen Dies at 42

January 13, 2016

By Fox News KDFW

She was hoping at least a thousand people would see it.
 
As of this week,  more than 51 Million people have seen Holley's story about being diagnosed with Breast Cancer at age 39. Then months after being given the all-clear, she learned her Breast Cancer had metastasized to her hip and spine.
 
When FOX 7 interviewed Kitchen last summer, the wife and mother of two told us she thought her double mastectomy and hysterectomy would have prevented further problems

Study identifies first potential targeted drug for triple-negative breast cancer and uncovers drug-resistance mechanism

January 8, 2016

By Dana Farber Cancer Institute

Anticipating cancer’s ability to bounce back from some therapies, scientists at Dana-Farber Cancer Institute have not only shown the promise of a new drug for a form of breast cancer, but have also uncovered a mechanism by which the cancer can outmaneuver the drug.

Epigenetic regulation of metastatic breast cancer progression may guide prognosis and future therapy

January 7, 2016

By Medical Express

Researchers have identified a gene called serum deprivation response (SDPR) and the mechanisms by which this gene is down-regulated, or silenced, in breast cancer cells promoting tumor spread.

Immunotherapy Is Game-Changer for Oncology

January 1, 2016

By Medpage

(Medpage requires a one-time free registration--well worth doing)New immunotherapy drugs to treat a wide swathe of cancers, are the game changers of 2015, according to dozens of oncologists who responded to MedPage Today.
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