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Carboplatin Role in Triple-Negative Breast Cancer Unresolved

December 15, 2015

By MedPag Today Charles Bankhead

The relationship between pathologic complete response and survival in triple negative breast cancer remained murky as two different randomized studies arrived at somewhat different conclusions.

Pembrolizumab Continues to Show Promise in Breast Cancer

December 13, 2015

By OncLive

"Based on these data, we believe that further investigation of immune therapies in ER+/HER- breast cancer, particularly using combination therapies that can expand the T-cell compartment, is warranted," lead researcher Hope S. Rugo, MD

Small Study Shows Immunotherapy Effective in Metastatic Breast Cancer Subset

December 11, 2015

By Cure Today Silas Inman

Treatment with the immunotherapy avelumab demonstrated promising overall response rates (ORR) for patients with PD-L1–positive metastatic breast cancer, particularly for those with triple-negative disease.

Recent Clinical Findings for Targeting CDK 4/6 in Breast Cancer

December 11, 2015

By Cancer Therapy Advisor Bryant Furlow

Palbociclib in combination with letrozole and now fulvestrant demonstrated significant clinical activity over endocrine therapy alone in advanced ER+ breast cancer and is the first approved CDK inhibitor,” Dr Finn said. “The combination was generally well tolerated, with uncomplicated neutropenia as the most frequent adverse event.”

ASCO Clinical Practice Guideline: Use of Biomarkers to Guide Systemic Therapy for Women With Metastatic Breast Cancer

December 11, 2015

By Matthew Stenger The ASCO Post

ASCO has issued a clinical practice guideline on the use of biomarkers to guide decisions on systemic therapy in women with metastatic breast cancer.

POINT: HER2-Targeted Combinations in Advanced HER2-Positive Breast Cancer

December 10, 2015

By Shom Goel, MD and Eric P. Winer, MD

The primary goals when treating patients with metastatic breast cancer are to improve both duration and quality of life.

Clinical trial explores treatment for metastases while continuing overall breast cancer therapy

December 9, 2015

By Medical Express

An ongoing phase IIR/III clinical trial presented at the 2015 San Antonio Breast Cancer Symposium seeks to answer an important question in the treatment of early metastatic breast cancer: Should surgery or stereotactic body radiation be used...

Women with Stage 4 breast cancer survive longer with surgery, study shows

December 4, 2015

By Lenny Bernstein, Washington Post

Over the past few decades, as breast cancer has increasingly been treated as a systemic disease, the number of surgeries performed on the most serious cases has plummeted.

Amy Robach on What Life After Breast Cancer Is Really Like

November 30, 2015

By Amy Rohrbach, Health Magazine

It’s been nearly two years since Good Morning America anchor Amy Robach announced her breast cancer diagnosis on live TV, following an on-air mammogram that colleague Robin Roberts urged her to get. In Amy’s new memoir, Better ($27, amazon.com), she writes candidly about her mastectomy, chemotherapy, and recovery over the next 12 months. In this excerpt from the book’s last chapter, she reflects on her new “normal” and what it’s like to live with the odds of a recurrence.

For women who’ve been successfully treated for breast cancer, there is a 30 percent chance that the disease will come back. There’s also something called an “Onco Score,” which weighs the details of each case to arrive at an individual’s specific odds of a recurrence. My Onco Score predicts my chances of bad news at 16 percent. But as my brother explained to me, the odds for any given individual are either 100 percent of zero percent. That’s because, where it counts, each of us is a population of one.

The disease gets cut out and blasted and poisoned away, and then you sit and wait. Doctors say, “You’re going to be fine,” but it really breaks down into survival rates at five years and survival rates at ten years. If breast cancer metastasizes, it’s terminal. I’ve always been a very positive person, even during my divorce and earlier medical issues. I’m like Orphan Annie, I guess, always believing that everything’s going to be better tomorrow, even when it’s hitting the fan today.

Big Changes Coming in Treatment of Triple-Negative Breast Cancer

November 30, 2015

By Silas Inman, CURE magazine

The treatment paradigm for patients with triple-negative breast cancer (TNBC) is set to undergo a dramatic transformation, as standard chemotherapeutic approaches are perfected and novel antibody-drug conjugates (ADCs) are developed. Kimberly Blackwell addressed this topic at the 2015 Chemotherapy Foundation Symposium, a meeting of over 1,000 oncologists and oncology professionals in New York City in November. - See more

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