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Amy Robach on What Life After Breast Cancer Is Really Like

November 30, 2015

By Amy Rohrbach, Health Magazine

It’s been nearly two years since Good Morning America anchor Amy Robach announced her breast cancer diagnosis on live TV, following an on-air mammogram that colleague Robin Roberts urged her to get. In Amy’s new memoir, Better ($27, amazon.com), she writes candidly about her mastectomy, chemotherapy, and recovery over the next 12 months. In this excerpt from the book’s last chapter, she reflects on her new “normal” and what it’s like to live with the odds of a recurrence.

For women who’ve been successfully treated for breast cancer, there is a 30 percent chance that the disease will come back. There’s also something called an “Onco Score,” which weighs the details of each case to arrive at an individual’s specific odds of a recurrence. My Onco Score predicts my chances of bad news at 16 percent. But as my brother explained to me, the odds for any given individual are either 100 percent of zero percent. That’s because, where it counts, each of us is a population of one.

The disease gets cut out and blasted and poisoned away, and then you sit and wait. Doctors say, “You’re going to be fine,” but it really breaks down into survival rates at five years and survival rates at ten years. If breast cancer metastasizes, it’s terminal. I’ve always been a very positive person, even during my divorce and earlier medical issues. I’m like Orphan Annie, I guess, always believing that everything’s going to be better tomorrow, even when it’s hitting the fan today.

Big Changes Coming in Treatment of Triple-Negative Breast Cancer

November 30, 2015

By Silas Inman, CURE magazine

The treatment paradigm for patients with triple-negative breast cancer (TNBC) is set to undergo a dramatic transformation, as standard chemotherapeutic approaches are perfected and novel antibody-drug conjugates (ADCs) are developed. Kimberly Blackwell addressed this topic at the 2015 Chemotherapy Foundation Symposium, a meeting of over 1,000 oncologists and oncology professionals in New York City in November. - See more

Cell-to-cell communication in cancer: workshop report

November 27, 2015

By Nature.com

The Memorial Sloan Kettering Cancer Center, in collaboration with the Breast Cancer Research Foundation and the National Cancer Institute, co-organized a workshop as an opportunity for leading researchers in their respective fields to present and discuss scientific research highlights relevant to the utilization of techniques and technologies for studying cell-to-cell communications in cancer.

Markers Could Predict Risk of Brain Metastasis in Breast Cancer Patients

November 22, 2015

By CancerNetwork

Serum matrix metalloproteinase 9 (MMP-9) and HER2 extra-cellular domain (HER2-ECD) might be predictive biomarkers for the metastasis of breast cancer to the brain

Blood Draw Could Detect AI Resistance in Breast Cancer

November 20, 2015

By CancerNetwork

Researchers in the United Kingdom have developed a sensitive blood-based assay that can detect mutations in the estrogen receptor gene ESR1, a known mechanism of resistance to aromatase inhibitors (AIs), in the circulating tumor DNA of patients with hormone receptor–positive breast cancer.

Medicine: Eyes on the target

November 19, 2015

By nature.com

Today, many patients with HER2-positive tumours are essentially having their cancer eradicated by receiving a double-hit of targeted therapy before surgery. Even patients diagnosed with late-stage, metastatic disease — once seen as an imminent death sentence — are living much longer than ever before.

Cancer Biomarker Researcher Brings Team to Houston Methodist

November 14, 2015

By news wise

Marchetti’s team also has identified biomarkers that could one day lead to a CTC biomarker test that may guide the treatment of brain metastatic breast cancer in patients.

Study of breast cancer metastasis upends conventional wisdom, suggesting new treatment strategy

November 13, 2015

By Medical Express

Breast cancer cells do not undergo a commonly accepted transformation in order to spread to distant organs such as the lungs, Weill Cornell Medicine investigators have found in a new study.

Living With Metastatic Breast Cancer: On Borrowed Time

November 13, 2015

By MedicalResearch.com Interview with: Shirley Mertz

MBCN President Shirley Mertz offers some insights on the realities of living with Stage IV breast cancer in this interview. "Scientists do not know why the disease returns as metastatic disease, and yet women are made to feel that a Stage IV diagnosis is their fault," says Shirley.

Cancer metastasis video wins AAMC top prize

November 12, 2015

By Woodruff Health Sciences Center

In a new video, Winship Cancer Institute researchers shows how they're isolating and studying the behavior of "leader" cells that may be the key to cancer metastasis.
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