Lifetime risk of developing invasive breast cancer
- 1 in 8 [ACS, 2011-2012]
- Risk in 1975: 1 in 11
| By Age | Probability of developing breast cancer in the next 10 years | |
| as a % | as 1 in xx number | |
| 20 | .06% | 1 in 1681 |
| 30 | .43 | 1 in 232 |
| 40 | 1.45 | 1 in 69 |
| 50 | 2.38 | 1 in 42 |
| 60 | 3.45 | 1 in 29 |
| 70 | 3.74 | 1 in 27 |
| Lifetime Risk | 12.15 | 1 in 8 |
Risk factors
- Age (95% diagnosed after age 40; median age at diagnosis is 61)
- Being female (99% of cases are female; 1% male)
- BRCA gene mutations (1% of the female population)
- 60% lifetime risk of getting breast cancer
- 15-40% risk of getting ovarian cancer (compared to 1.4% risk in general population)
- Ashkenazi Jews (originally from Eastern Europe):higher risk
- 10 times more likely to have BRCA mutation (2.6% vs .2% for general population)
- But, only 7% of BC in Ashkenazi Jews is caused by BRCA mutations
- Family history – first degree relative (10% of all bc)
- Exposure to radiation at early age
- DCIS or other cancers
- Dense breasts
